Years of research
In collaboration with the Swiss Federal Institute of Technology de Lausanne (EPFL)
Powered by Mitopure®
No other supplement does this.
Award-winning clinically proven Urolithin A products.
Shop now#1 Doctor Recommended
Urolithin A Brand
Urolithin A Brand
★★★★★4.7 from 13181 reviews · 95% recommend
“Revitalized mind and body” · Amanda K
“A lifesaver” · Catherine J
“Convenient and effective” · Antoine V
Time to give your cells new life with high-performance products powered by Mitopure®, our powerful ingredient that unlocks a precise dose of the rare Urolithin A molecule and promotes healthy aging.
Human clinical trials
Completed and ongoing gold-standard clinical trials involving over 2000 participants
Studies on Urolithin A
Scientists have extensively explored the effectiveness of Urolithin A on health
Patents
Our proprietary ingredient Mitopure® is protected under 80 patents
Mitopure®Gold-standard clinical trial
+39%
Increase in mitophagy
39%30%20%10%
PlaceboMitopure® Supplements
+12%
Muscle strength
128.22.2-3.8
PlaceboMitopure® Supplements
6×
Urolithin A glucuronide (ng/ml)
480360240120
Pomegranate juiceMitopure® Supplements
Compare us to other
The Ultimate Longevity Powerhouse
mitopure®
|
NAD+
|
CoQ10
|
Creatine
|
Spermidine
|
|
|---|---|---|---|---|---|
| Directly activates mitophagy Mitophagy is the body's natural process for replacing damaged mitochondria with new, healthy ones. Urolithin A is clinically shown to trigger this process directly, while other supplements support mitochondrial health in indirect ways.* |
|
|
|
|
Partial |
| Targets a root cause of age-related cellular energy decline Aging is associated with declining mitochondrial function and the buildup of damaged mitochondria in the cells. Urolithin A acts on a root cause of age-related cellular energy decline by activating the body’s natural renewal process and recycling dysfunctional mitochondria into new, healthy ones.* |
|
Partial | Partial |
|
Partial |
| Benefits without changing exercise routine Unlike many supplements that primarily support performance during exercise, Urolithin A has been shown to enhance mitochondrial and muscle health even without a change in physical activity.* |
|
|
|
|
|
| Complete human clinical trials Multiple human clinical trials have demonstrated Urolithin A’s safety and effectiveness.* While there is human evidence for some popular longevity supplements, others are primarily validated by preclinical research, early-stage human trials or animal studies. |
|
Limited |
|
|
Limited |
|
mitopure®
|
Other Urolithin A
|
|
|---|---|---|
| 5 Gold Standard Clinical Trials Mitopure is the only clinically tested and validated form of Urolithin A, with safety and efficacy demonstrated across multiple placebo-controlled trials. |
|
|
| #1 Doctor-Recommended Brand Leading scientists and doctors recommend and endorse Mitopure, validating its superior quality, efficacy and safety. |
|
|
| NSF Certified Mitopure consistently surpasses quality and safety standards, making it a trusted choice for athletes. |
|
|
| Exceptional purity Mitopure ensures top-tier purity (>98%), guaranteeing both quality and effectiveness. |
|
Unknown |
| Patented Urolithin A 18 years of rigorous research and >80 global patents. |
|
|
Loved by our community
“Excellent supplement”
Debra K
Verified buyer 
“Increased Strength and Energy”
Margaret M
Verified buyer
“My stamina is returning....”
Carol B
Verified buyer
Find out why the experts trust Urolithin A from Timeline
“This is a supplement I use myself everyday to be as healthy as I can, for as long as I can.”
Dr. Mark Hyman, MD
Functional Medicine Physician, 15x New York Times Bestselling Author
“No other supplement does what Timeline can. It is an amazing advance for muscle health and longevity.”
Dr. Gabrielle Lyon
Founder Institute for Muscle-Centric Medicine®
“The latest clinical studies crystallize how Mitopure can be a real game-changer for human health.”
Dr. Johan Auwerx MD, PhD
Scientific Advisor
“Mitochondrial decline is a key hallmark of aging and Mitopure is one of the most promising compounds in our field”
Eric Verdin, MD
CEO Buck Institute for Research on Aging, Scientific Advisor